Summarize the pathophysiology of Peptic Ulcer Disease

Summarize the pathophysiology of Peptic Ulcer Disease

enry, a 58 y/o male, recently reports waking up in the middle of the night with burning abdominal pain. Symptoms occur several nights a week with occasional discomfort in the middle of the afternoon. A bland diet or drinking milk do seem to help and spicy foods aggregate the symptoms.

PMH: non-contributory

SH: Works in a grocery store, divorced, non-smoker, drinks 1-2 beers/day

Allergies: none

Meds: 1 325mg ASA daily for cardiovascular prevention

ROS:

Constitutional: Decrease appetite and 5% weight loss; denies fever
ENT: Denies sore throat or drainage
Lungs: Occasional dry cough at night
Heart: Mid sternum chest burning intermittently
Abdomen: Epigastric burning and tenderness, denies constipation or diarrhea

Initial Post: Summarize the pathophysiology of Peptic Ulcer Disease as compared to GERD and explain which one his symptoms most closely represent. Support with evidence